Author

Jia Gu

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Open access Oct 2026

UniMedSeg: Unified Multi-Modal Medical Image Segmentation via Uncertainty-Guided Encoding and Frequency-Spatial Dual-Prompt Decoding

This framework incorporates modality-aware adaptation, cross-layer uncertainty-guided encoding, and a frequency-spatial dual-prompt decoder, wherein the progressive uncertainty propagation mechanism of the encoder suppresses misleading cross-modal features, whereas the decoder disentangles anatomical structure and boun...

Jing-Ling Zhang, Shu-Ting Zheng, Xiang-Fei Liu et al. · bioRxiv · 0 citations

Open access Sep 2026

High‐Concordance Detection Across Diverse Biospecimens EGFR Mutation in a Large‐Scale NSCLC Cohort Using Droplet Digital PCR and Next‐Generation Sequencing

Accurate detection and quantification of EGFR mutations are essential for molecular stratification in non‐small cell lung cancer (NSCLC). While next‐generation sequencing (NGS) enables comprehensive genomic profiling, droplet digital PCR (ddPCR) offers high sensitivity for predefined mutations. Large‐scale evaluati...

Ming Liu, Lin-Ping Lu, Qifang Lei et al. · iMetaMed · 0 citations

Open access Jul 2026

Geometric-aware deep learning for deciphering tissue structure from spatially resolved transcriptomics.

SpatialGEO, a geometric-aware deep learning framework that integrates gene expression profiles with spatial coordinates to generate biologically meaningful low-dimensional embeddings, enabling the dissection of complex tissue architectures, achieves superior performance in tissue structure dissection and data denoising...

Xing-Yi Li, Xiang-Ting Jia, Dong-Min Zhao et al. · Communications Biology · 1 citation