Author

Jiliang Fang

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Clinical trial Open access Aug 2026

Rs-fMRI reveals that taVNS improves cognitive and emotional function in mild cognitive impairment by reconfiguration of “sensory relay-salience-default” cross-network effective connectivity: a randomized, double-blind, sham-controlled trial

Background Transcutaneous auricular vagus nerve stimulation (taVNS) is a promising noninvasive intervention for mild cognitive impairment (MCI), but its clinical efficacy and network-level mechanisms remain unclear. Methods In this prospective, randomized, sham-controlled, parallel-group trial, 60 patients with MCI wer...

Tianjiao Xu, Chun-Lei Guo, Lei Zhang et al. · Frontiers in Neurology · 0 citations

Editorial Open access Jul 2026

Exploring brain-gut interaction mechanisms in Transcutaneous auricular Vagus Nerve stimulation for Major Depressive Disorder

The gut microbiota is intricately implicated in the pathogenesis of Major Depressive Disorder (MDD), with the vagus nerve serving as a key regulatory bridge. Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) has emerged as a promising non-invasive therapeutic strategy for MDD by modulating the gut-brain axis, ye...

Yue Ma, Jifei Sun, Chunlei Guo et al. · BMC Psychiatry · 0 citations