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Sep 2026

Novel linear B-cell epitopes mapping with monoclonal antibodies to VP3 protein from bluetongue virus serotype 1.

Bluetongue is an infectious disease affecting domestic and wild ruminants that is caused by bluetongue virus (BTV). VP3 is the major component of the BTV inner capsid and a structural protein that is essential for viral maturation. The B-cell epitopes on BTV-1 VP3 that are recognized by the humoral immune response rema...

Fan-Hua Meng, Yu-Qing Song, Xuan-Ying Wang et al. · 0 citations
Open access Sep 2026

Mapping of three novel linear B-cell epitopes on the VP7 protein of epizootic hemorrhagic disease virus with monoclonal antibodies

Epizootic hemorrhagic disease virus (EHDV) is an important Orbivirus transmitted by culicoides midges. EHDV poses a significant threat to ruminant production worldwide. The VP7 protein is a highly conserved, group-specific antigen of EHDV, which serves as a key target for serological diagnosis. In this study, the recom...

Xin-Bing Hu, Yun-Ru Zhong, Ying-Juan He et al. · 0 citations
Open access Sep 2026

Genotype II Live‐Attenuated ASFV Vaccine Bearing 24 Genes Deletion in 3 Independent Regions Is Able to Provide Complete Protection Against Homologous Lethal Challenge

African swine fever (ASF) is an acute, febrile, and highly contagious infectious disease of swine with the etiological agent of African swine fever virus (ASFV). The mortality rate of virulent strains is as high as 100%. Strengthening biosafety is so far the most effective way to prevent and control ASF. Therefore, it...

Fan Xu, Wen Dang, Yu Du et al. · 0 citations
Open access Jul 2026

MGF100 but not MGF300 family is a potential multigene-deleted target for ASFV attenuation and live attenuated vaccine development

The MGF100 family is a potential multigene-deleted target for ASFV live-attenuated vaccine development and was found to be capable of inducing a robust innate immune response in vitro and a consistent P30 antibody response in vivo.

Wen Dang, Fan Xu, Yu Du et al. · 0 citations

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