Author

Ji-Jia Hu

3 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Review Aug 2026

Senescent repair memory in chronic disease: failed resolution as a driver of persistent organ dysfunction.

Chronic diseases can continue to progress after the initiating insult has subsided, indicating that injured tissues may retain a persistent imprint of failed repair. Here, senescent repair memory refers to a tissue state in which transient repair-associated senescence fails to resolve and is maintained by persistent se...

Hong-Tu Hu, Rui Ji, Ji-Jia Hu · Ageing Research Reviews · 0 citations

Review Aug 2026

Drug failure in diabetic kidney disease: translational barriers, target validation and trial de-risking strategies.

Diabetic kidney disease (DKD) remains a difficult therapeutic setting in nephrology, metabolism and clinical pharmacology. Standard care has moved from glucose- and blood-pressure-centred treatment toward disease-modifying therapy built around renin-angiotensin-aldosterone system (RAAS) blockade, sodium-glucose cotrans...

Hong-Tu Hu, Suyue Hou, Wen-Jie Chen et al. · Biochemical Pharmacology · 0 citations

Oct 2026

SIRT3 regulates GLS1 K311 acetylation to restrain glutamate-driven ferroptosis in renal fibrosis.

Renal tubulointerstitial fibrosis is a final common pathway of chronic kidney disease (CKD), but the metabolic mechanisms linking mitochondrial dysfunction to ferroptotic tubular injury remain incompletely defined. We found that a SIRT3-GLS1-glutamate-p53/SLC7A11 pathway links mitochondrial deacetylation to ferroptosis...

Miao Yan, Hong-Tu Hu, Cheng Chen et al. · Cellular Signalling · 0 citations