Isopropoxate Exerts Neurotoxicity by Crossing the Blood-Brain Barrier and Mediating through Inflammation-Neurotransmitter Signaling Pathways.
Isopropoxate (IPPO), an emerging imidazole ester-type new psychoactive substance, poses potential risks to public health and the environment, yet its neurotoxic mechanisms remain poorly understood. In this study, 8-week-old C57BL/6J mice were used to evaluate the effects of IPPO on the blood-brain barrier (BBB), oxidat...