Author

Ji-Cun Zhu

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Open access Sep 2026

Microsatellite instability combined with PD-L1 expression in prognosis of gastric cancer: an integrated analysis based on individual patient data.

Objective This study aimed to systematically assess the predictive value of microsatellite instability (MSI) combined with programmed death-ligand 1 (PD-L1) expression for prognosis and immunotherapy response in patients with gastric cancer (GC). Methods An individual patient data (IPD) meta-analysis was performed in...

Ya-Jing Feng, Meng-Meng Yin, J. Chai et al. · Frontiers in Oncology · 0 citations

Open access Aug 2026

Life course adiposity and risk of incident osteoporosis: a prospective cohort study from the UK Biobank

Introduction Adiposity across the life course may influence osteoporosis (OP) risk, yet the relative contributions of early-life and adult adiposity, their trajectories, and underlying molecular mechanisms remain unclear. Methods We analyzed 357,903 participants from the UK Biobank with a median follow-up of 15.7 years...

Hui-Min Liu, Ji-Cun Zhu, Qiang Zhang et al. · Frontiers in Endocrinology · 0 citations