Simple Summary Certain aggressive cancers, such as sarcomas and brain gliomas, achieve cellular “immortality” by lengthening their telomeres using a survival mechanism called ALT. Currently, researchers look for specific DNA mutations to detect ALT, but this method is often insufficient for accurately predicting patien...
I. Armendáriz-Castillo, S. Guerrero, Andrés Herrera-Yela et al.· Biology· 0 citations
Alterations in gut microbial ecology have been linked to obesity, type 2 diabetes (T2D), and hypertension, but their biological significance remains difficult to separate from diet, medication use, adiposity, and other host factors. We synthesize evidence on intestinal barrier dysfunction, microbial translocation, low-...
Jhommara Bautista, Ronald Hernández-León, Alexandra S. Valencia-Valverde et al.· Frontiers in Endocrinology· 1 citation
The skin microbiome is an integral component of the cutaneous ecosystem and contributes to barrier, immune, and metabolic homeostasis. Available evidence is examined across three distinct levels: microbial community structure, functional activity, and host biological response. This ecological–functional distinction is...
Jhommara Bautista, Andrea Iñiguez-Ramírez, Jaime Andrés Villegas-Chávez et al.· Frontiers in Microbiology· 1 citation
This review critically synthesizes spatially resolved, single-cell and mechanistic evidence to determine when tumour-associated Tregs constitute active components of suppressive multicellular niches rather than merely correlates of immune exclusion.
Jhommara Bautista, Miranda Di Capua Delgado, Juliana Viteri-Recalde et al.· Frontiers in Cell and Develo...· 0 citations
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