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Jeyapal Vidhyadharan

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Open access Oct 2026

TSHR gene expression and mitochondrial-cardiac interactions as emerging predictors of cardiovascular risk in early thyroid dysfunction

Abstract Objectives To evaluate biochemical, hormonal, genetic, and mitochondrial alterations associated with cardiovascular risk in SCH, emphasizing the interplay between NT-proBNP, succinate dehydrogenase (SDH) complex activity, and thyroid-stimulating hormone receptor (TSHR) gene expression. Methods A case–control s...

Manjusha Kottola, Desigamani Kanniyappan, Damodaran Boopathi et al. · 0 citations
Open access Jul 2026

Association of APOE gene expression with thyroid dysfunction, inflammation, and nitrosative stress in cardiometabolic syndrome: a case–control study

CMS is characterized by the convergence of thyroid dysregulation, inflammation, oxidative stress, and increased ApoE gene expression, which highlights a coordinated molecular network underlying CMS and support the integration of molecular and inflammatory biomarkers into cardiometabolic risk assessment.

Tha-alnoorein Abdulla, T. Kumar D, J. Inbanathan et al. · 0 citations

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