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Jessica Regan

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Open access Sep 2026

A Selective PanK3 Activator Restores Coenzyme A in Cellular and Mouse Models of Pantothenate Kinase-Associated Neurodegeneration.

It is demonstrated that a lead VTAC compound, VTAC-2, restores CoA levels to wild-type levels both in cells and in mouse brain, making this compound an attractive candidate for clinical evaluation for the treatment of PKAN.

Jessica Regan, A. Pal, S. Gihaz et al. · 0 citations

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