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Author

Jessica Oliphant

2 papers indexed here

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Sep 2026

Beyond NAMs versus animal models: Context of use as the governing framework for integrated nonclinical strategies in drug development.

New approach methodologies (NAMs) originated in chemical hazard assessment, where two forces operate together: the scale of characterizing many substances, and a long-standing ethical and legal commitment to replacing animal testing. Drug development is weighted differently. It is a translational and decision problem a...

Stefano Gaburro, B. Berridge, Nicholas W. Kelley et al. · 0 citations
Open access Sep 2026

Integrated miR-omics and proteomics reveal the regulatory role of miR in protein networks associated with COVID-19 disease progression

Introduction While microRNA (miR) expression profiling has identified potential biomarkers in patients with COVID-19, the regulatory mechanisms by which miRs modulate disease severity remain poorly characterized. We performed integrated miR–proteome analysis to elucidate mechanistic relationships between miR regulation...

Kelly E. Mercer, Vikrant Vijay, Li-Rong Yu et al. · 0 citations

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