Dynamics of bicoid mRNA localisation and translation dictate morphogen gradient formation.
The transcription factor Bicoid (Bcd) protein guides early Drosophila patterning and is the best-characterised morphogen. The source of the morphogen, bcd mRNA, is maternally deposited during oogenesis and localised to the anterior pole. When and where Bcd protein is produced and how this protein gradient is dynamicall...
T. Athilingam, E. L. Wilby, P. Bensidoun et al.
· EMBO Journal · 0 citations