Development of a Recombinant O/CATHAY Topotype Foot-and-Mouth Disease Virus as a Resource for Vaccine Matching and Efficacy Evaluation
Foot-and-mouth disease virus serotype O remains a global threat, particularly the O/CATHAY topotype in East and Southeast Asia. Because timely access to emerging field isolates can be limited, reverse genetics provides a flexible approach for generating viruses representing selected circulating strains for vaccine matc...