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Author

Jens H. Kuhn

2 papers indexed here

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Open access Oct 2026

Early detection of immunoglobulin A against a vaccine backbone protein enables fast, durable, and objective identification of individuals vaccinated against Ebola virus

Summary Background rVSVΔG-ZEBOV-GP vaccine is recommended for prevention of Ebola virus (EBOV) infection and disease (EVD). However, breakthrough EBOV infections have been observed in vaccinees. Currently available diagnostic and research assays cannot reliably distinguish individuals vaccinated against Ebola virus fro...

Olivia Posadas, I. M. Berry, V. Callier et al. · 0 citations
Open access Sep 2025

High-throughput virus quantification using cytopathic effect area analysis

Traditional infectivity-based virion quantification methods, such as 50% tissue culture infectious dose (TCID50) and plaque assays, are typically performed in 6-, 12-, 24-, or 48-well cell culture plates and require manual work and analysis based on legacy protocols. Adaptation of these methods to high-throughput forma...

Michael J. Murphy, S. Mazur, Elena Postnikova et al. · 0 citations

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