Author

Jennifer W. Gin

2 papers indexed here

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Open access Oct 2026

Replacing anaerobic fermentation with reverse β-oxidation enables growth-coupled evolution for enhanced fatty-alcohol production

Engineering robust fermentation hosts remains a barrier to scalable biomanufacturing. In this work we replace canonical mixed-acid fermentation in Escherichia coli with a redox‑balanced reverse β‑oxidation (rBOX) pathway that produces medium‑chain fatty alcohols and is bioenergetically equivalent to ethanol ferme...

Bridgie Cawthon, Aidan E. Cowan, Zen Yoshikawa et al. · Nature Communications · 0 citations

Open access Oct 2026

Orchestrating polyketide synthase-derived aldehyde metabolism for Streptomyces biomanufacturing.

Advances in metabolic engineering have enabled the integration of diverse non-native reactions into microbial hosts, providing sustainable alternatives to petrochemical manufacturing. We previously developed a modular polyketide synthase (PKS)-based platform in Streptomyces albus for producing 17 diols, amino alcohols,...

Q. Dan, Xi-Na Wang, Yan Chiu et al. · Metabolic Engineering · 0 citations