Background/Aim: Severe acute meningoencephalitis is a life-threatening neurological condition frequently associated with excessive inflammation, immune dysregulation, and secondary immune dysfunction. Immune exhaustion and abnormal immune cell remodeling may contribute to persistent inflammation and impaired recovery....
Chang-Hao Wu, Jeng-Wei Lu, Yi-Jung Ho et al.· In Vivo· 0 citations
Dengue virus (DENV), an enveloped mosquito-borne flavivirus, is the causative agent of dengue and prevalent in tropical and subtropical regions. Severe cases can progress to dengue hemorrhagic fever or shock syndrome, posing significant public health challenges. In the absence of specific antiviral drugs, antimicrobial...
Ting-Chun Lin, Jeng-Wei Lu, Chia-Hsin Liu et al.· Antiviral Research· 0 citations
Investigation of the antiviral properties and underlying mechanism of trehalose 6‐monolaurate against Sindbis virus establishes TML as a host‐directed inhibitor acting at post‐entry stages of alphavirus replication and underscores its potential as a lead scaffold for the development of therapeutics against mosquito‐bor...
Jeng-Wei Lu, M. Helal, Guan-Chiun Lee et al.· Journal of Medical Virology· 0 citations
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