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Author

Jemma Gullick

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Open access Jul 2026

Mechanism for Aromatic Nitration Catalyzed by Cytochrome P450 Enzymes from Rufomycin Biosynthesis

These experiments revealed the intimate and necessary involvement of a histidine residue within the pentapeptide substrate of RufO in supporting effective nitration, with the protonation state of the intermediate compound II proposed to influence the production of nitrated tyrosine over unwanted nitrate formation.

Alicia M. Kirk, Jemma Gullick, Yong-Wei Zhao et al. · 2 citations
Open access Aug 2026

Assessing Vancomycin‐Formyl Peptide Conjugate Binding to the Surface of Resistant Staphylococcus aureus via Flow Cytometry

Flow cytometry is used to quantify the binding of vancomycin=fPep conjugates to S. aureus clinical isolates and will assist in future studies to understand how attached fPeps and other immune signalling cargoes can stimulate innate immune cell activation leading to bacterial phagocytosis.

Winfrey P Y Hoo, Jemma Gullick, Ryan Leung et al. · 0 citations
Open access Jul 2026

A Machine Learning-Based Genome Mining Approach Reveals Unprecedented Biarylitide Diversity

This study repurposed a machine learning algorithm to comprehensively chart the biosynthetic space of the biarylitides, including variation of precursor motifs, P450, and additional modifying enzymes, which yielded 277 biarylitide biosynthetic gene clusters (BGCs).

Leo Padva, Jemma Gullick, Friederike Biermann et al. · 1 citation

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