Author

Jeffery A. Noble

3 papers indexed here

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Open access Sep 2026

Design and synthesis of reagents for generation and characterization of high-affinity antibodies for a Staphylococcus aureus serotype 8 disaccharide.

Staphylococcus aureus is a common, opportunistic pathogen, and drug resistance of this organism continues to rise. Substantial efforts have been made to generate vaccines that provide long-lasting protection; however, these have fallen short. High-affinity antibodies could represent a useful treatment modality, taking...

S. Mata, S. Deng, Jeffery A. Noble et al. · European Journal of Cell Bio... · 0 citations

Open access Aug 2026

The Qβ bacteriophage nanoparticle contributes to the adjuvanticity of antiglycan vaccines through a unique inflammatory pathway.

Current glycoconjugate vaccines often fail to induce durable B cell memory or to provide sufficiently high-affinity antibodies limiting their utility for prophylactic protection against most bacterial and fungal pathogens. We address this limitation by engineering a chemically functionalized protein nanoparticle vaccin...

Kenna Nagy, Jeffery A. Noble, S. Deng et al. · Journal of Immunology · 0 citations

Open access Aug 2026

Immunization with the Tc85-Derived Peptide Displayed on Virus-like Particles Confers Protection against Trypanosoma cruzi Infection

Findings identify PP7-Tc85pep as a potent, multifunctional epitope capable of engaging innate and adaptive immune pathways, and support further development of Tc85pep-based epitope vaccines as a next-generation strategy for Chagas disease prevention.

Ugochukwu Oduwe, Giorgi Kenkebashvili, Syed Uddin et al. · ACS Omega · 0 citations