An integrated computational strategy for processing nanopore protein ionic current signals from synthetic protein constructs containing all 20 amino acids in controlled sequence contexts is developed, using a profile hidden Markov model to capture sequential structure of protein translocation.
Andrew J. Stein, Neda Ghohabi-Esfahani, Stuart G. Akeson et al.· bioRxiv· 0 citations
Protein engineering appears to be entering a golden age, defined by a rapidly accelerating pace of progress, even as significant challenges in design, screening, and real-world application remain.
H. Ai, Frances H. Arnold, Doug Barrick et al.· Protein engineering, design...· 0 citations
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