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Author

Jeff Nivala

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Open access Oct 2026

A strategy for ionic current analysis of nanopore protein readouts

An integrated computational strategy for processing nanopore protein ionic current signals from synthetic protein constructs containing all 20 amino acids in controlled sequence contexts is developed, using a profile hidden Markov model to capture sequential structure of protein translocation.

Andrew J. Stein, Neda Ghohabi-Esfahani, Stuart G. Akeson et al. · 0 citations
Review Open access Jul 2026

Protein engineering: status report

Protein engineering appears to be entering a golden age, defined by a rapidly accelerating pace of progress, even as significant challenges in design, screening, and real-world application remain.

H. Ai, Frances H. Arnold, Doug Barrick et al. · 0 citations

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