Author

Jean-Baptiste Pingault

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Open access Oct 2026

Estimating direct and indirect genetic effects on emerging variation in depressive symptoms in early adolescence: a trio polygenic score analysis in the MoBa cohort : Author list.

Early adolescence is a common period of onset for depressive symptoms. In part, this may reflect a developmental expression of individuals' genetic propensities as they undergo physiological and hormonal changes and interact with new environments. Many commonly proposed mechanisms assume direct effects of an individual...

M. Bazezew, B. Glaser, L. Hegemann et al. · European Child and Adolescen... · 0 citations

Open access Oct 2026

Genetic risk of psychopathology predicts environmental risk

Environmental risk factors for psychosis and psychopathology are often treated as non-genetic, although many are partly heritable or correlated with genetically influenced traits. We tested nine polygenic scores against 49 environmental-risk factors in 307,493 UK Biobank participants without recorded schizophrenia, b...

Adam Socrates, Jessie R. Baldwin, Robin M. Murray et al. · Schizophrenia · 0 citations

Open access Jul 2026

DNA methylation as proxy of genetic, prenatal and perinatal psychiatric risk factors

Background. Cord blood DNA methylation profile scores (MPSs) based on genetic and pre-/perinatal risk factors for neurodevelopmental conditions (NDCs) may capture downstream biological effects and help understand how combined exposure signals contribute to NDC risk. Methods. Using data from two longitudinal birth cohor...

Elena Isaevska, Rosa H. Mulder, I. Schuurmans et al. · medRxiv · 0 citations