Semi-synthesis of indole-fused taraxerone derivatives from Rhizophora stylosa Griff.: anti-bacterial study and docking insights
A series of novel semisynthetic indole-fused taraxerone derivatives (2a–2f) were synthesised from taraxerone isolated from Rhizophora stylosa Griff. and characterised by 1H NMR,13C NMR, and HRMS analyses. Incorporation of the pharmacologically important indole moiety was aimed at enhancing protein-ligand interactions a...