Cannabinoids as Context-Dependent Modulators of the Adenosine A3 Receptors: Potential Orthosteric and Allosteric Mechanisms.
CBG is identified as an effective enhancer of adenosine potency at human A3R, suggesting it stabilizes an occupancy-dependent secondary pose that fine-tunes the orthosteric agonist-receptor interaction network.
Joan Serrano-Marín, Gemma Navarro, V. S. de Medina et al.
· Pharmacological Research · 0 citations