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Jasper L. Tyler

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Open access Sep 2026

Aromatic Pummerer-Promoted Stereospecific Cross-Coupling of Thiazoles With Boronic Esters.

Thiazoles are ubiquitous motifs in bioactive molecules, making strategies for the stereospecific installation of chiral C(sp3)-rich substituents on this scaffold particularly valuable for drug discovery. However, achieving such transformations remains nontrivial, as conventional C(sp2)-C(sp3) cross-coupling approaches...

Mark John P. Mandigma, Julien Lefranc, Louise Eagling et al. · 0 citations

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