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A human pluripotent stem cell tri-culture platform to elucidate microglial regulation of retinal ganglion cells in neuroinflammation
This study established human pluripotent stem cell-derived co-culture systems incorporating microglia, astrocytes, and RGCs to explore how microglia shape RGC growth and maturation under physiological conditions and dissect the cellular interactions driving RGC vulnerability in inflammatory conditions relevant to optic...