Open access
Jul 2026
Conserved folds enable immune antagonism across the tree of life
The Viral Compendium is established, a database of over 350,000 proteins and domains from eukaryotic, bacterial, and archaeal viruses, to demonstrate that pathogen immune evasion is built upon conserved structural building blocks, revealing unified mechanisms and effectors of immune antagonism spanning all domains of life.
L. Profeta, Erin E. Doherty, Johanna M. Ebner et al.
· bioRxiv · 0 citations