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Jason G. Williams

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Open access Sep 2026

Molecular architecture and assembly of the human RNA Degradosome

The PNPase exoribonuclease interacts with the SUV3 helicase to form the human RNA Degradosome responsible for processive mitochondrial RNA turnover and quality control. Although structural data reveals the trimeric PNPase architecture along with the monomeric and dimeric states of SUV3, the molecular basis of their ass...

Justin A. Gee, Jason G. Williams, Monica C. Pillon · 0 citations

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