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Author

Jaroslava Guzikova

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Open access Sep 2026

Bardoxolone methyl induces mitochondrial dysfunction, activation of the cytosolic stress response, and increased chaperone capacity in SH-SY5Y cells. Focus on mitochondrial protease LONP1.

The results indicate that mitochondrial dysfunction, activation of cytosolic stress response, and an increase in chaperone capacity elicited by CDDO-Me could be attributed to CDDO-Me's ability to inhibit LONP1 protease.

Ľuboš Hudák, A. Evinova, Monika Liskova et al. · 0 citations

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