Janna E. Jernigan Posey

The limited role of RGS10 on NFκB and cytokine transcript levels in peritoneal macrophages under the influence of opioid analgesics

Regulator of G-protein signaling 10 (RGS10) has been shown to regulate multiple inflammatory pathways relevant to disease pathogenesis. Of particular importance is the ability of RGS10 to negatively regulate the NFkB pathway, a prominent pro-inflammatory pathway implicated in multiple inflammatory disease phenotypes. H...