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Engineering Pluripotent Stem Cells-Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro-Topographical Cues.
Inner ear organoids (IEOs) derived from pluripotent stem cells (PSCs) provide a promising platform for modeling neurosensory disorders and hearing loss; however, conventional systems often exhibit substantial structural variability, incomplete maturation, and limited reproducibility due to insufficient control of early...
Regenerative Nano-scaffolds for Tissue Engineering: From Bench to Clinical Translation
A multifunctional, collagen-coated polylactic-co-glycolic acid nanotopographical scaffold that mimics the native extracellular matrix to enhance soft- and hard-tissue regeneration and support its potential as a clinically relevant platform for regenerative medicine.