Author

Janet L. Oblinger

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Open access Jul 2026

Single-cell and spatial omics reveals region-specific plasticity and therapeutic vulnerabilities in metastatic high-risk neuroblastoma

It is identified that lymph node metastases in high-risk neuroblastomas display distinctive cellular heterogeneity and plasticity, marked by mesenchymal-like and stem-like states and heightened epithelial-to-mesenchymal transition activity compared to primary adrenal tumors.

Laiman Wu, Janet L. Oblinger, Da-Zhuan Xin et al. · Science Advances · 0 citations