Single-cell transcriptomics uncovers persistent hepatic immunometabolic remodeling following SARS-CoV-2 infection in obese hosts
SARS-CoV-2 infection affects multiple organs, and chronic post-viral tissue injury is often associated with persistent immune dysregulation. Obesity and related metabolic disorders are major risk factors for severe COVID-19 and post-acute sequelae of SARS-CoV-2 infection (PASC), including liver dysfunction. To define h...