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Jana Shen

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Open access Oct 2026

Activation pathway of the human voltage-gated proton channel

Many protein functions are coupled to proton transfer, yet the underlying mechanisms remain extremely difficult to resolve by experiment or conventional molecular dynamics (MD) simulations. The human voltage-gated proton channel HV1 (hHV1) plays key roles in human physiology, but how voltage and pH together drive its a...

Ming-Zhe Shen, Daniel Kortzak, Christophe Jardin et al. · 0 citations

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