Jan Kunzmann

Synthesis of DNA Building Blocks With Thiazole Fluorophores for Fluorescent Readout by Excimers and Energy Transfer

Two new charged DNA building blocks were synthesized with thiazole orange (TO) and dibenzothiazole (DB) as fluorescent DNA base surrogates. They promote excimer formation and energy transfer within DNA architectures, because they were incorporated as fluorophore pairs into oligonucleotides such that they interact in an...