Author

Jan K. Buitelaar

3 papers indexed here

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Open access Oct 2026

Inhibitory control and error processing in Obsessive-Compulsive Disorder: A mega-analysis of task-based fMRI data by the ENIGMA-OCD consortium.

OBJECTIVE Obsessive-compulsive disorder (OCD) is a chronic condition in which impaired inhibitory control and excessive error monitoring may contribute to maintenance of obsessions and compulsions. This mega-analysis investigates neural activation during response inhibition and error processing using adult (OCD=563; co...

N. Džinalija, O. A. van den Heuvel, H. B. Simpson et al. · Biological Psychiatry · 0 citations

Review Oct 2026

Adult Attention Deficit-Hyperactivity Disorder.

Attention deficit-hyperactivity disorder (ADHD) is a medical condition that is present in approximately 2.5% of adults worldwide and manifests in a variety of different ways across the lifespan. Adults with ADHD often have coexisting psychiatric disorders such as anxiety, mood, sleep, substance use, and personality dis...

Jan K. Buitelaar, Jeffrey H. Newcorn · New England Journal of Medic... · 0 citations

Open access Sep 2026

Disrupting peripheral serotonin synthesis drives sex-specific alterations in sociability and cognition, and reshapes the gut-immune-brain axis.

Serotonin (5-HT) regulates neurodevelopment and behavior. Whereas central 5-HT is synthesized by tryptophan hydroxylase (TPH)-2, the TPH1 isoform produces 5-HT peripherally. Although these systems are anatomically segregated, TPH1 gene polymorphisms have been linked to neuropsychiatric vulnerability, suggesting that pe...

Rogério C. R. Castro, N. Alenina, E. E. Natasha et al. · Brain, behavior, and immunit... · 0 citations