Author

James J. McCormick

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Open access Oct 2026

Effects of 24-h sleep deprivation on circulating irisin, BDNF, and soluble klotho responses during exercise in the heat in young and older males.

Sleep deprivation and heat stress commonly coexist in occupational, athletic, and environmental settings and may disproportionately increase physiological strain in older adults. We examined whether 24-h sleep deprivation alters circulating biomarkers linked to proposed roles in metabolic adaptation (irisin), neurophys...

Joel M. Garrett, James J. McCormick, Nicholas J. Koetje et al. · American Journal of Physiolo... · 0 citations

Oct 2026

Sleep Deprivation Selectively Alters Cellular Stress Responses During Exercise in the Heat in Young and Older Males.

It is indicated that 24 h of sleep deprivation does not broadly alter markers of macroautophagy during exercise-heat stress but selectively modifies cellular stress pathways in older males, with distinct responses observed in young and older males.

James J. McCormick, Kelli E. McCormick, Nicholas J. Koetje et al. · Medicine & Science in Sports... · 0 citations

Open access Aug 2026

Short-term passive heat acclimation modulates autophagy and cellular stress responses in older active adults.

BACKGROUND Age-related impairments in thermoregulatory and cardiovascular function contribute to a heightened vulnerability to heat-related morbidity and mortality. While passive heat acclimation is highly effective at improving heat loss mechanisms in older adults, its effects on autophagic regulation remain unknown....

James J. McCormick, Kelli E. McCormick, Kristina-Marie T. Janetos et al. · Journal of Sport and Health... · 0 citations