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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

James J. De Voss

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Open access Jul 2026

Mechanism for Aromatic Nitration Catalyzed by Cytochrome P450 Enzymes from Rufomycin Biosynthesis

These experiments revealed the intimate and necessary involvement of a histidine residue within the pentapeptide substrate of RufO in supporting effective nitration, with the protonation state of the intermediate compound II proposed to influence the production of nitrated tyrosine over unwanted nitrate formation.

Alicia M. Kirk, Jemma Gullick, Yong-Wei Zhao et al. · 2 citations
Open access Jul 2026

A Machine Learning-Based Genome Mining Approach Reveals Unprecedented Biarylitide Diversity

This study repurposed a machine learning algorithm to comprehensively chart the biosynthetic space of the biarylitides, including variation of precursor motifs, P450, and additional modifying enzymes, which yielded 277 biarylitide biosynthetic gene clusters (BGCs).

Leo Padva, Jemma Gullick, Friederike Biermann et al. · 1 citation

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