James E. Crowe

Development and application of nbLIBRA-seq for high-throughput discovery of antigen-specific nanobodies.

Nanobodies are of high interest in many fields of medicine and biotechnology, although nanobody discovery has been limited by laborious screening techniques. Here, we demonstrate the successful adaptation of linking B cell receptor to antigen specificity through sequencing (LIBRA-seq) to immunized alpacas for the rapid...