Author

James D. Allen

2 papers indexed here

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Open access Sep 2026

Computationally Optimized H1 and H3 Hemagglutinin Messenger RNA Vaccines Confer Broad Protective Immunity Against Modern Influenza Viruses

These findings demonstrate that COBRA HA encoding mRNA vaccines can effectively leverage immunological memory while expanding responses to conserved HA epitopes, supporting improved protection against antigenically drifted strains and represents a promising strategy for next-generation influenza vaccination.

James D. Allen, Jessica M. Medina, Camila Caetano et al. · bioRxiv · 0 citations

Open access Aug 2026

Design and characterization of broadly protective influenza A(H3N2) vaccine candidates using protein language models

It is demonstrated that an integrated generation–selection strategy can enhance vaccine coverage across current and future A(H3N2) seasons and may be applicable to other influenza subtypes.

Victoria R. Howard, James D. Allen, Matthew H. Thomas et al. · bioRxiv · 0 citations