Open access
Aug 2026
Irregular nucleosome positioning governs a crystalline to liquid-like phase transition and tunes chromatin accessibility
Using synthetic chromatin fibres assembled from physiologically relevant DNA sequences, it is shown that nucleosome positioning dictates the material state of chromatin, indicating that nucleosome positioning tunes chromatin toward or away from critical structural states that couple genome protection, chromatin dynamic...
Waad Albawardi, Matthew Thomas, Gert-Jan Kuijntjes et al.
· bioRxiv · 0 citations