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Author

Jakub Kleinrok

3 papers indexed here

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Review Open access Oct 2026

The Changing Global Epidemiology of Early-Onset Colorectal Cancer: Incidence Trends, Modifiable Risk Factors, and Future Burden Projections

Early-onset colorectal cancer (EOCRC), defined as colorectal cancer diagnosed before age 50, has become an increasing global public health concern. Incidence rates have risen among younger adults in many countries, despite stable or declining rates in older populations. This review examines global EOCRC epidemiology, p...

Kacper Wrzosek, Agata Koba, Pola Bakalczuk et al. · 0 citations
Review Open access Oct 2026

Nephrotic range proteinuria and rapid progression to end-stage kidney disease in seronegative pauci-immune necrotizing glomerulonephritis masked by cutaneous lesions: a case-based review

Antineutrophil cytoplasmic antibodies (ANCA)-negative pauci-immune necrotizing glomerulonephritis (PING) is a rare entity, representing a distinct subset of small-vessel vasculitis. The absence of ANCA does not exclude the diagnosis, and clinical suspicion should remain high in the presence of compatible systemic and r...

Aleksandra Gałan, Filip Koszałka, I. Zakrocka et al. · 0 citations
Review Open access Oct 2026

Oncolytic Viruses as In Situ Cancer Vaccines: Tumor Microenvironment Remodeling, Checkpoint Inhibitor Synergy, and Biomarker-Guided Clinical Translation

Oncolytic viruses (OVs) are increasingly viewed not only as tumor-lysing agents but also as immunotherapeutic platforms capable of functioning as in situ cancer vaccines. By selectively infecting malignant cells, inducing immunogenic cell death, releasing tumor-associated antigens and danger signals, and activating inn...

Kamil Rogalski, Michał Iwaszko, Anna Kuraś et al. · 0 citations

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