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Jae-Young Je

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Open access Oct 2026

Nrf2/HO-1 Activation Mediates the Anti-Adipogenic and Browning Effects of Phloroglucinol in 3T3-L1 Adipocytes

Phloroglucinol (PG) is a naturally occurring phenolic compound and the fundamental monomeric unit of marine phlorotannins, yet its effects on adipocyte differentiation and browning remain incompletely understood. This study investigated whether PG inhibits adipogenesis and induces browning markers in 3T3-L1 adipocytes...

I. T. Suryaningtyas, R. Pangestuti, Won-Kyo Jung et al. · 0 citations
Oct 2026

Lysine-Proline-Valine attenuates oxidized low-density lipoprotein-induced foam cell formation and inflammatory responses in RAW264.7 macrophages.

Atherosclerosis develops through oxidative stress and inflammatory responses induced by oxidized low-density lipoprotein (oxLDL), and excessive lipid accumulation in macrophages accelerates disease progression by facilitating foam cell formation. In this study, we investigated the protective effects of the α-melanocyte...

Ji-Jiang Bai, Ri-Won Kim, Yong Li et al. · 0 citations
Review Open access Aug 2026

Gut microbiota-targeted bioactive peptides as emerging axis in nutritional therapeutics: trends, challenges, and prospects

The review indicates the promising potential of BAPs as microbiota-based, innovative, and useful agents in nutritional therapy and addresses novel ways to increase the activity of BAPs with respect to stability and delivery.

Brij Pal Singh, Prabhashis Bose, Jae-Young Je · 1 citation

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