Phase 2 Evaluation of two GEO-CM04S1 Dose Levels Shows Comparable Safety and Broad Immunogenicity.
BACKGROUND GEO-CM04S1 is a synthetic modified vaccinia Ankara (sMVA)-based SARS-CoV-2 vaccine expressing Spike (S) and Nucleocapsid (N) antigens derived from the ancestral Wuhan-Hu-1 reference strain. This phase 2 study evaluated the safety and immunogenicity of two GEO-CM04S1 dose levels administered as a single boost...