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Jacob S. Shine

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#protein folding Open access Oct 2026

DMT1 Facilitates Heme-iron Absorption in Rats and Mice.

Mechanisms of heme-iron (HI) absorption remain uncertain. Heme is probably absorbed by receptor-mediated endocytosis; iron is then enzymatically liberated from heme within endosomes, or in the cytosol. If heme is catabolized in endosomes, a transporter, such as DMT1, would be required to export ionic iron into the cyto...

Yue He, Jacob S. Shine, S. Sriram et al. · 0 citations

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