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BACKGROUND Pneumococcal meningitis remains a major threat, with high fatality rates and long-term sequelae, despite advances in vaccination and treatment. We aimed to examine the associations between pneumococcal serotypes, Global Pneumococcal Sequence Cluster (GPSC), antimicrobial resistance, source of infection, and...
Gliotoxin inhibited planktonic growth and significantly reduced the biomass and viability of biofilms in a concentration-dependent manner, and its combination with conventional antibiotics showed strong synergy, drastically decreasing bacterial survival.
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