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J. Wrammert

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Open access Sep 2026

Longitudinal dynamics and lineage cross-reactivity of the human antibody response to West Nile virus

ABSTRACT West Nile virus (WNV) is an emerging/re-emerging flavivirus representing one of the major global causes of mosquito-borne encephalitis, yet no approved therapeutics or vaccines currently exist. To characterize the kinetics of WNV-specific immunity, we evaluated the humoral response in a longitudinal cohort of...

Austin G. Leach, Ling-Ling Xu, Shilu Malakar et al. · 0 citations
#protein folding Open access Aug 2026

Immunological imprinting shapes the cross-reactive antibody responses to the KP.2 and LP.8.1 vaccine doses

Data indicate the KP.2 mRNA vaccine generates durable, cross-reactive responses against current Omicron subvariants, however, ongoing spike evolution impacts the neutralization of emerging lineages, highlighting the need for continued viral monitoring and timely vaccine updates.

Sanjeev Kumar, Li-Lin Lai, M. Ellis et al. · 0 citations

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