PURPOSE
Immune checkpoint inhibitors (ICIs) have significantly altered the natural history of microsatellite instability high (MSI-H) colorectal cancer (mCRC). For microsatellite stable (MSS) refractory mCRC, ICIs recently demonstrated efficacy signals in patients without liver metastases. This study evaluated combined...
Leontios Pappas, J. Koenig, B. Yeap et al.· Clinical Cancer Research· 0 citations
Despite recent advances in RAS-directed therapy, pancreatic ductal adenocarcinoma (PDAC) remains highly lethal. Surgical resection, chemotherapy, and radiotherapy continue to anchor treatment, but therapeutic resistance is pervasive, and most patients succumb to treatment-refractory residual disease. Advances in sing...
D. Olgun, Beatrice Awasthi, N. Lester et al.· Cancer Research· 0 citations
OBJECTIVE
To determine actual 5-year survival after neoadjuvant therapy and resection for pancreatic ductal adenocarcinoma (PDAC).
BACKGROUND
Long-term outcomes after neoadjuvant therapy and resection for PDAC remain poorly defined, as current knowledge largely relies on actuarial estimates.
METHODS
Retrospective c...
Federico De Stefano, G. Belfiori, Nathaniel F. Wu et al.· Annals of Surgery· 0 citations
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