Micro-modulation of the intra-structural environment in electrospun drug delivery systems: effects on drug release and hydrolytic degradation.
Poor aqueous solubility can limit drug release from biodegradable implants. We developed a multifunctional dual-jet electrospun drug-delivery system (DDS) designed to accelerate the release of poorly water-soluble bioactive substances. Its principle is based on introducing the drug-carrying matrix and release-rate modi...