Abstract Clinical syndromes of frontotemporal dementia present both distinct and overlapping neuroimaging abnormalities and, consequently, domains of impairment. The aim of this study was to determine how well covariance patterns from multiple neuroimaging modalities discriminate across clinical frontotemporal dementia...
Irene Sintini, Neha Singh-Reilly, Farwa Ali et al.· Brain Communications· 0 citations
Background/Objectives: The role of iron in Alzheimer’s disease (AD) and frontotemporal lobar degeneration (FTLD) has been debated. However, the effects of iron on protein burden in these diseases remain poorly elucidated. We hypothesized that there is an association between iron deposition and tau and beta-amyloid depo...
Rodolfo Gabriel Gatto, Hossam Youssef, Gökhan Uruk et al.· Brain Science· 0 citations
White matter microstructural disruption is a dominant imaging signature of CBS and is more closely linked to gray matter volume loss than to measurable uptake on tau PET, while dMRI, particularly MD and ICVF, may provide greatest sensitivity for detecting disease-related changes in CBS.
Yu-Qi Tian, Ryota Satoh, V. Lowe et al.· medRxiv· 0 citations
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