Author

J. Weiss

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Oct 2026

B-219 High seroprevalence but low frequency of intrathecal anti-Epstein-Barr virus IgG suggests a unique role of Epstein-Barr virus infection in multiple sclerosis

Multiple sclerosis (MS) is strongly associated with high anti-Epstein-Barr virus (EBV) IgG seroprevalence. Many patients with MS have an intrathecal production of antiviral antibodies, which can be detected by elevated antibody indices (AI) [1,2]. In fact, the detection of intrathecal antibodies against measles,...

J. Weiss, F. Pache, C. Otto et al. · Clinical Chemistry · 0 citations

Oct 2026

B-218 Improved and customized dengue serodiagnostics through combined NS1/IgM testing and novel dual-cut-off IgG ELISA

Accurate diagnostics of dengue virus (DENV) infection are essential for patient management, outbreak control, and vaccine implementation. Serological testing plays a key role, especially when molecular assays are unavailable or viremia subsides; yet, cross-reactivity with other flaviviruses remains a challenge. T...

J. Weiss, S. Saschenbrecker, Nadja Muigg et al. · Clinical Chemistry · 0 citations

Oct 2026

B-217 Newly developed ELISA for detection of circulating calprotectin in serum and plasma

Circulating calprotectin is a biomarker that reflects activation of the innate immune system. Measuring its concentration in serum or plasma is relevant for diagnosis and monitoring of systemic inflammations, autoimmune diseases, and infections. Here we introduce a newly developed enzyme-linked immunosorbent assa...

J. Weiss, Kathrin Hoffmann, V. Herbst et al. · Clinical Chemistry · 0 citations