J. W. Lee

Kinetics of local C3 production orchestrates neutrophil recruitment in lung injury.

Complement component 3 (C3) is crucial for host defense against bacteria. While the liver is the primary source of circulating C3, local C3 production at barrier surfaces such as the lung is key in early responses. Yet, how local complement-mediated responses are initiated at mucosal barriers-and how locally-derived C3...