Open access
Aug 2026
Network-level functional connectivity is associated with longitudinal tau accumulation and amyloid-dependent cognitive decline in preclinical Alzheimer’s disease
Lower static connectivity across multiple large-scale networks was associated with faster longitudinal tau accumulation and, selectively in individuals with elevated amyloid burden, with accelerated cognitive decline, and these associations were not observed for time-varying connectivity.
Mohammadali Javanray, Jonathan Gallego-Rudolf, Y. Yakoub et al.
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